ABSTRACT
RESUMEN Se reporta el uso del crosslinking como tratamiento de la queratitis por Acanthamoeba en una serie de 7 pacientes quienes acudieron al Servicio de Córnea por queratitis multitratadas. Se les realizó biopsia corneal, la cual se cultivó en solución de Page. Los pacientes fueron tratados con un protocolo de PACK-CXL durante más de 5 minutos y fueron sometidos a la exposición a la luz UV-A. El edema del nuevo epitelio era de 2 cruces a las 24 horas, y desapareció a las dos semanas del procedimiento en todos los casos. El porcentaje de desepitelización basal al momento del diagnóstico fue de 75,7 por ciento. La agudeza visual mejor corregida fue de entre 20/20 y 20/30. Se concluye que el uso de crosslinking en pacientes con Acanthamoeba en fases inicales pudiera ser una opción terapéutica segura y efectiva(AU)
ABSTRACT A report is presented of the use of crosslinking as treatment for Acanthamoeba keratitis in a series of 7 patients attending the Cornea Service for multitreated keratitis. Corneal biopsy was performed, which was cultured in Page solution. The patients were treated with a PACK-CXL protocol for more than 5 minutes and subjected to UV-A light exposure. Edema of the new epithelium was 2 crosses at 24 hours and disappeared 2 weeks after the procedure in all cases. Basal de-epithelialization percentage at diagnosis was 75.7 percent. Best corrected visual acuity ranged between 20/20 and 20/30. It is concluded that the use of crosslinking in patients with Acanthamoeba keratitis in its initial stages could be a safe and effective therapeutic option(AU)
Subject(s)
Humans , Adult , Middle Aged , Aged , Acanthamoeba/cytology , Acanthamoeba Keratitis/diagnosis , Acanthamoeba Keratitis/drug therapy , Research Report , Review Literature as Topic , Databases, BibliographicSubject(s)
Humans , Cataract , Cataract Extraction , Endophthalmitis , Pseudomonas , Pseudomonas aeruginosa , BlindnessABSTRACT
Introduction: Patients with diabetic macular edema can develop fundus autofluorescence alterations; thus far, these alterations have been more widely studied with scanning or confocal laser systems. Objective: To describe and classify fundus autofluorescence abnormal patterns in patients with diabetic macular edema using the fundus autofluorescence system with a flash camera. Method: Observational, retrospective, cross-sectional, descriptive study. Fundus autofluorescence digital images of non-comparative cases with untreated diabetic macular edema, obtained and stored with a flash camera system, were assessed. Inter-observer variability was evaluated. Results: 37 eyes of 20 patients were included. Lens opacity was the most common cause of inadequate image quality. Five different fundus autofluorescence patterns were observed: decreased (13%), normal (40%), single-spot hyper-autofluorescent (17 %), multiple-spot hyper-autofluorescent (22 %) and plaque-like hyper-autofluorescent (8 %). The kappa coefficient was 0.906 (p = 0.000). Conclusions: Different fundus autofluorescence phenotypic patterns are observed with flash camera systems in patients with diabetic macular edema. A more accurate phenotypic classification could help establish prognostic factors for visual loss or for the design of clinical trials for diabetic macular edema.
Subject(s)
Humans , Male , Female , Middle Aged , Macular Edema/diagnostic imaging , Diabetic Retinopathy/diagnostic imaging , Optical Imaging/instrumentation , Optical Imaging/methods , Phenotype , Observer Variation , Macular Edema/classification , Macular Edema/etiology , Cross-Sectional Studies , Retrospective Studies , Diabetes Mellitus, Type 2/complications , Diabetic Retinopathy/classification , Diabetic Retinopathy/complications , MexicoABSTRACT
La oclusión de la vena hemirretiniana (OVHR) tiene características clínicas peculiares que comparte tanto con una oclusión de vena central de la retina (OVCR) como con oclusión de rama venosa retiniana (ORVR), las cuales se han descrito poco en la literatura, además de que su manejo no está aún protocolizado. Se realizó un estudio retrospectivo reuniendo los expedientes de los casos vistos desde enero de 1995 hasta mayo de 1998. Evaluando el cuadro clínico, la evolución y el manejo final de 36 pacientes y en total 37 ojos. El objetivo del estudio es conocer la prevalencia de la OVHR en nuestro hospital así como su curso clínico, pronóstico, complicaciones más frecuentes y respuesta al tratamiento con fotocoagulación